What is tissue perfusion and oxygenation


At centers such as the University Hospital Erlangen, reconstruction operations are routinely performed with the body's own tissue and microsurgical vascular connections. For this purpose, the removed tissue is transplanted from one part of the body to another and reconnected to the bloodstream. "However, the time from removal to reinsertion of the tissue is still a critical phase," says Prof. Dr. Dr. H. c. Raymund Horch, Director of the Plastic and Hand Surgery Clinic at Erlangen University Hospital. Depending on the type of tissue used, the time that the tissue can survive without a continuous supply of oxygen and then be successfully reconnected varies from one to several hours. "If there are unforeseen delays in this phase, this can be critical for the success of the operation," says Prof. Horch. In order to optimize and improve this phase, and thus to increase the safety of such operations, the working group of Dr. Müller-Seubert and Prof. Horch have been working on methods of so-called extracorporeal perfusion for years.

To support their work, the researchers have now received research funding from the Research Foundation Medicine at the University Clinic Erlangen, made possible by a generous donation from Borghild Marshall. "It is a wonderful experience to see that people are so committed to translational, patient-oriented basic research and then unselfishly make their contribution to improving medicine. The Medical Research Foundation established at the University Hospital Erlangen is increasing such research funds , extremely helpful, "says Prof. Horch.

Additional Information:

Prof. Dr. Dr. H. c. Raymund Horch
Phone: 09131 85-33277
Email: raymund.horchuk-erlangen.de